Browsing by Author "Kuloglu, Zarife"

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    Angiodysplasia as a cause of severe hematochezia in a child with end-stage renal failure
    (Taylor & Francis, 2011-02-01) Kuloglu, Zarife; Özçakar, Z. Birsin; Kansu, Aydan; Üstündağ, Gonca; Ekim, Mesiha; Altugan, F. Şemsa; Kendirli, Tanıl; Çınar, Kubilay; Yalçınkaya, Fatoş; Tıp Fakültesi
    Angiodysplasia is a frequent cause of gastrointestinal bleeding in adults with chronic renal failure (CRF); however, there is no data about this association in children. The mechanism of this association is not known. We report a 4.5-year-old boy with CRF presenting with hematochezia due to colonic angiodysplasia. He was on hemodialysis for the previous 9 months. Treatment with argon plasma coagulation (APC) was commenced following a short course of octreotide therapy. During the 3 years of follow-up, no occult or gross bleeding occurred. This case illustrates that octreotide and APC therapy seems to be useful for arresting bleeding from angiodysplasia and prevention of recurrent bleeding in children with CRF.
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    Mesalamine Intolerance in Three Children with Crohn's Disease
    (2016) Kirsaclioglu, Ceyda Tuna; Kuloglu, Zarife; Ustundag, Gonca; Kansu, Aydan; Ince, Erdal; Ensari, Arzu; Girgin, Nurten; TIP FAKÜLTESİ
    Objective: To present the mesalamine-induced acute exacerbation of symptoms and inflammatory markers in children with Crohn's disease (CD). Clinical Presentation and Intervention: Three children who presented with CD had acute exacerbation of colitis symptoms or elevated inflammatory markers when mesalamine was added to treatment while tapering/ceasing steroid treatment. While on steroid treatment, the patients maintained clinical and laboratory remission, but with the initiation of mesalamine treatment, they had abdominal pain and bloody mucoid diarrhoea and/or elevation of white blood cell count, C-reactive protein level and erythrocyte sedimentation rate. Bacterial pathogens were excluded from the urine, throat and blood cultures, parasites with stool examination, viral pathogens with serology. Within 3-7 days after the mesalamine treatment had been stopped, the patients showed improvement of colitis symptoms and normalisation of white blood cell count, C-reactive protein level and erythrocyte sedimentation rate. Conclusion: In this study mesalamine mimicked CD relapse in children with CD while tapering or after stopping steroid treatment. Awareness of this side effect of mesalamine could prevent a misdiagnosis of steroid dependency. (C) 2015 S. Karger AG, Basel