Polymorphisms of TLR1, TLR4 and SLC11A1 Genes in Some Cattle Breeds Reared in Turkey

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dc.contributor.authorArslan, Korhan
dc.contributor.departmentZiraat Fakültesitr_TR
dc.date.accessioned2021-09-28T06:23:02Z
dc.date.available2021-09-28T06:23:02Z
dc.date.issued2018-12-05
dc.description.abstractThe objective of this study was to examine the allelic and genotypic profiles of four SNPs of bovine Toll-Like receptor 1 (TLR1), Toll-Like Receptor 4 (TLR4) and Solute Linkete Carier 11A1 (SLC11A1) genes in Holstein, two Turkish native breeds and their crossbreds in Turkey. For this purpose, a total of 1023 cattle from Holstein (HL, n= 410), Anatolian Black (AB, n= 106), East Anatolian Red (EAR, n= 84), Anatolian Black Crossbreed (ABC, n= 124) and East Anatolian Red crossbreed (EARC, n= 299) breeds were examined for four SNPs. Samples were genotyped using by the PCR-RFLP method. According to the TLR1 (+1380) SNP, EAR was in Hardy-Weinberg equilibrium (HWE) while the AB, HL and native crossbreeds were deviated from HWE. All cattle breeds were in HWE for the TLR1 (+1596) SNP. In terms of TLR4 (+10) SNP, the CC genotype had the highest frequency in HL and native crossbreeds whereas the AB and EAR breeds were monomorphic and only CC genotype was found these breeds. According to the SLC11A1 (+1066) SNP, the CC genotype had the highest while the GG genotype frequency the lowest in all breeds. In addition EAR breed was in HWE while the AB, HL and native crossbreeds deviated from HWE.tr_TR
dc.identifier.endpage553tr_TR
dc.identifier.issn/e-issn2148-9297
dc.identifier.issue4tr_TR
dc.identifier.startpage547tr_TR
dc.identifier.urihttps://doi.org/10.15832/ankutbd.349728tr_TR
dc.identifier.urihttp://hdl.handle.net/20.500.12575/74963
dc.identifier.volume24tr_TR
dc.language.isoentr_TR
dc.publisherAnkara Üniversitesitr_TR
dc.relation.isversionof10.15832/ankutbd.349728tr_TR
dc.relation.journalTarım Bilimleri Dergisitr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıtr_TR
dc.subjectPolymorphismtr_TR
dc.subjectTurkish native cattletr_TR
dc.subjectToll-like receptortr_TR
dc.titlePolymorphisms of TLR1, TLR4 and SLC11A1 Genes in Some Cattle Breeds Reared in Turkeytr_TR
dc.typeArticletr_TR

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Cilt:24 Sayı:04 (2018)