A multicenter study of patients with adult-onset Still's disease compared with systemic juvenile idiopathic arthritis

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dc.contributor.authorKınıklı, Gülay
dc.contributor.authorIDhttp://orcid.org/0000-0002-4006-1022tr_TR
dc.contributor.departmentTıp Fakültesitr_TR
dc.contributor.otherTürkçapar, Nuran
dc.contributor.otherDüzgün, Nurşen
dc.contributor.otherÖlmez, Ümit
dc.contributor.otherTiryaki-Aydintuǧ, Olcay
dc.contributor.otherTurgay, Murat
dc.contributor.otherDuman, Murat
dc.date.accessioned2020-03-17T08:30:04Z
dc.date.available2020-03-17T08:30:04Z
dc.date.issued2006
dc.description.abstractAdult-onset Still's disease (AOSD) has often been regarded as the adult spectrum of systemic juvenile idiopathic arthritis (sJIA). The present study aims to compare the clinical and laboratory features, the disease course and the response to treatment in patients having AOSD with those having sJIA. Retrospective review of all available data that were filled out by adult and paediatric rheumatologists from six centers using a standard data extraction form was performed. A total of 95 patients with AOSD and 25 patients with sJIA were recruited for the study. The frequency of fever, rash, myalgia, weight loss and sore throat was higher in patients with AOSD. The pattern of joint involvement differed slightly. Laboratory findings were similar in both groups, except that liver dysfunction and neutrophilia were more common among adults. A multiphasic pattern dominated the childhood cases, whereas the most frequent course was a chronic one in adults. Corticosteroids and methotrexate were the most commonly employed therapy; however, chloroquine was another popular therapy in the adult group. We showed a difference in the rate of clinical and laboratory features between patients with AOSD and those with sJIA. AOSD and sJIA may still be the same disease, and children may simply be reacting differently as the result of the first encounter of the putative antigens with the immune system. © Clinical Rheumatology 2006.tr_TR
dc.description.indexScopus
dc.description.indexPubmed
dc.identifier.endpage644tr_TR
dc.identifier.issn/e-issn0770-3198
dc.identifier.issn/e-issn1434-9949
dc.identifier.issue5tr_TR
dc.identifier.startpage639tr_TR
dc.identifier.urihttps://doi.org/10.1007/s10067-005-0138-5tr_TR
dc.identifier.urihttp://hdl.handle.net/20.500.12575/70677
dc.identifier.volume25tr_TR
dc.language.isoentr_TR
dc.relation.isversionof10.1007/s10067-005-0138-5tr_TR
dc.relation.journalClinical Rheumatologytr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıtr_TR
dc.subjectAdult-onset Still's diseasetr_TR
dc.subjectSystemic juvenile idiopathic arthritistr_TR
dc.titleA multicenter study of patients with adult-onset Still's disease compared with systemic juvenile idiopathic arthritistr_TR
dc.typeArticletr_TR

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