Menopoz ve fitoöstrozenler
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2006
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Sağlık Bilimleri Enstitüsü
Abstract
Menopause and PhytoestrogensPhytoestrogens are plant compounds that have estrogenic andantiestrogenic properties. Molecular and cellular experiments made in humanand animals showed that phytoestrogens are useful in menopausalsymptoms, cardiovascular diseases, osteoporosis and various cancers(breast, colon and prostate carcinomas).Variety of phytoestrogens and their metabolic products have been identifiedin man and animals (in bile, urine, semen, blood, feces). They are classifieldas isoflavones, coumestans, prenyl flavonoit and lignans. Most importantphytoestrogens are isoflavones. Most important resources are Glycine max,Linum usitatissimum, Cimicifuga racemosa and Trifolium pratense. Inpopulations that consume these plants, cardiovascular diseases,osteoporotic fractures, menopausal symptom and some carcinomas are seenless often. In postmenopausal and perimenopausal periods. They are used inalleviating vasomotor symptoms.Food supports and phytopharmaceutical forms have been developed.Phytoestrogens are suggested for use, especially in menopause, and otherdiseases.Key Words : Phytoestrogens, estrogenic/antiestrogenic activity, menopauseosteoporosis97
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Eczacılık ve Farmakoloji